Che-1/AATF: a critical co-factor for both wild type- and mutant-p53 proteins

The p53 protein is a key player in a wide range of protein networks that allow the state of good health of the cell. Not surprisingly, mutations of the p53 gene are one of the most common alterations associated to cancer cells. Mutated forms of p53 (mtp53) not only lose the ability to protect the in...

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Bibliographic Details
Main Authors: Tiziana eBruno, Simona eIezzi, Maurizio eFanciulli
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Oncology
Subjects:
p53
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00034/full