Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress.

Casticin is one of the main active components obtained from Fructus Viticis and has been reported to exert anti-carcinogenic activity on a variety of cancer cells but the precise mechanism underlying this activity remains unclear.Apoptotic activities of casticin (1.0 µmol/l) and TRAIL (25, 50 ng/ml)...

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Bibliographic Details
Main Authors: Yuan Zhou, Li Tian, Lingzhi Long, Meifang Quan, Fei Liu, Jianguo Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3594187?pdf=render