Inference of Gene Coexpression Networks by Integrative Analysis across Microarray Experiments

We improve the reliability of detecting coexpressed gene pairs from microarray data by introducing a novel probe-level quality-weighted similarity measure for combining data across different Affymetrix experiments. In construction of gene coexpression networks, the proposed procedure is less sensiti...

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Bibliographic Details
Main Authors: Elo Laura L., Aittokallio Tero
Format: Article
Language:English
Published: De Gruyter 2006-12-01
Series:Journal of Integrative Bioinformatics
Online Access:https://doi.org/10.1515/jib-2006-33