<i>N</i>-(2-Hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1<i>H</i>- benzimidazol-1-yl)propyl]piperidine-4-Carboxamide (D2AAK4), a Multi-Target Ligand of Aminergic GPCRs, as a Potential Antipsychotic

<i>N</i>-(2-Hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1<i>H</i>- benzimidazol-1-yl)propyl]piperidine-4-Carboxamide (D2AAK4), a Multi-Target Ligand of Aminergic GPCRs, as a Potential Antipsychotic

<i>N</i>-(2-hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1<i>H</i>-benzimidazol -1-yl)propyl]piperidine-4-carboxamide (D2AAK4) is a multitarget ligand of aminergic G protein-coupled receptors (GPCRs) identified in structure-based virtual screening. Here we present detailed in vitro...

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Bibliographic Details
Main Authors: Agnieszka A. Kaczor, Katarzyna M. Targowska-Duda, Andrea G. Silva, Magda Kondej, Grażyna Biała, Marián Castro
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
antipsychotics
behavioral studies
drug design
in vitro studies
molecular modeling
schizophrenia
Online Access:https://www.mdpi.com/2218-273X/10/2/349

Internet

https://www.mdpi.com/2218-273X/10/2/349

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