MicroRNA-375 regulates oocyte in vitro maturation by targeting ADAMTS1 and PGR in bovine cumulus cells

MicroRNAs (miRNAs) have attracted increasing attention for their function in oocyte in vitro maturation (IVM). In this study, we aimed to explore the functional role and underlying mechanism of miR-375 in oocyte IVM. Cumulus-oocyte complexes (COCs) were cultured in standard cell culture conditions u...

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Bibliographic Details
Main Authors: Jianrui Zhang, Yichun Guan, Chunyan Shen, Luwen Zhang, Xingling Wang
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
PGR
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219325880