Sensitive Tumorigenic Potential Evaluation of Adult Human Multipotent Neural Cells Immortalized by hTERT Gene Transduction.

Stem cells and therapeutic genes are emerging as a new therapeutic approach to treat various neurodegenerative diseases with few effective treatment options. However, potential formation of tumors by stem cells has hampered their clinical application. Moreover, adequate preclinical platforms to prec...

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Bibliographic Details
Main Authors: Kee Hang Lee, Hyun Nam, Da Eun Jeong, Sung Soo Kim, Hye Jin Song, Hee Jang Pyeon, Kyeongjin Kang, Seung-Cheol Hong, Do-Hyun Nam, Kyeung Min Joo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4938125?pdf=render