Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Leads to Loss of DNA Methylation in Neuronal Genes

Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Leads to Loss of DNA Methylation in Neuronal Genes

Dyskinesias are characterized by abnormal repetitive involuntary movements due to dysfunctional neuronal activity. Although levodopa-induced dyskinesia, characterized by tic-like abnormal involuntary movements, has no clinical treatment for Parkinson’s disease patients, animal studies indicate that...

Full description

Bibliographic Details
Main Authors: Luca Pagliaroli, Abel Fothi, Ester Nespoli, Istvan Liko, Borbala Veto, Piroska Devay, Flora Szeri, Bastian Hengerer, Csaba Barta, Tamas Aranyi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
dyskinesia
levodopa
Riluzole
abnormal involuntary movements
Tourette syndrome
epigenetics
Online Access:https://www.mdpi.com/2073-4409/10/6/1442

Internet

https://www.mdpi.com/2073-4409/10/6/1442

Similar Items