When, why and how tumour clonal diversity predicts survival
Abstract The utility of intratumour heterogeneity as a prognostic biomarker is the subject of ongoing clinical investigation. However, the relationship between this marker and its clinical impact is mediated by an evolutionary process that is not well understood. Here, we employ a spatial computatio...
Main Authors: | Robert Noble, John T. Burley, Cécile Le Sueur, Michael E. Hochberg |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-08-01
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Series: | Evolutionary Applications |
Subjects: | |
Online Access: | https://doi.org/10.1111/eva.13057 |
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