When, why and how tumour clonal diversity predicts survival

Abstract The utility of intratumour heterogeneity as a prognostic biomarker is the subject of ongoing clinical investigation. However, the relationship between this marker and its clinical impact is mediated by an evolutionary process that is not well understood. Here, we employ a spatial computatio...

Full description

Bibliographic Details
Main Authors: Robert Noble, John T. Burley, Cécile Le Sueur, Michael E. Hochberg
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Evolutionary Applications
Subjects:
Online Access:https://doi.org/10.1111/eva.13057