Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

Abstract Background Extracellular vesicles (EVs) are nano-sized particles secreted by most cells. EVs carry nucleic acids that hold promise as potential biomarkers in various diseases. Human immunodeficiency virus type 1 (HIV) infects CD4+ T cells and induces immune dysfunction, inflammation, and EV...

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Bibliographic Details
Main Authors: Sukrutha Chettimada, David R. Lorenz, Vikas Misra, Steven M. Wolinsky, Dana Gabuzda
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Immunology
Subjects:
HIV
Online Access:http://link.springer.com/article/10.1186/s12865-020-00386-5