The Relationships among Tryptophan, Kynurenine, Indoleamine 2,3-Dioxygenase, Depression, and Neuropsychological Performance

It has been suggested that the metabolic enzyme indoleamine 2,3-dioxygenase (IDO) is a biological mediator of inflammation related to the psychopathology of depression, with a Kynurenine (KYN) increase in the Tryptophan (TRP) metabolic pathway, resulting in reduced Serotonin. In this study, we exami...

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Bibliographic Details
Main Authors: Knut A. Hestad, Knut Engedal, Jon E. Whist, Per G. Farup
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Psychology
Subjects:
IDO
Online Access:http://journal.frontiersin.org/article/10.3389/fpsyg.2017.01561/full