PCSK9: A New Target for Lipid-Lowering Therapy

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a crucial protein in low density lipoprotein cholesterol (LDL-C) metabolism. It binds the low density lipoprotein receptor (LDLR) and returns the LDLR to degradation in the lysosome and thereby raises the plasma levels of LDL-C. Gain-of-functi...

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Bibliographic Details
Main Author: Nutjaree Jeenduang
Format: Article
Language:English
Published: Prince of Songkla University 2014-04-01
Series:Journal of Health Science and Medical Research (JHSMR)
Subjects:
Online Access:https://www.jhsmr.org/index.php/jhsmr/article/view/208