PCSK9: A New Target for Lipid-Lowering Therapy
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a crucial protein in low density lipoprotein cholesterol (LDL-C) metabolism. It binds the low density lipoprotein receptor (LDLR) and returns the LDLR to degradation in the lysosome and thereby raises the plasma levels of LDL-C. Gain-of-functi...
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Format: | Article |
Language: | English |
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Prince of Songkla University
2014-04-01
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Series: | Journal of Health Science and Medical Research (JHSMR) |
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Online Access: | https://www.jhsmr.org/index.php/jhsmr/article/view/208 |