Marine Natural Products with P-Glycoprotein Inhibitor Properties

P-glycoprotein (P-gp) is a protein belonging to the ATP-binding cassette (ABC) transporters superfamily that has clinical relevance due to its role in drug metabolism and multi-drug resistance (MDR) in several human pathogens and diseases. P-gp is a major cause of drug resistance in cancer, parasiti...

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Bibliographic Details
Main Authors: Dioxelis Lopez, Sergio Martinez-Luis
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/1/525