Marine Natural Products with P-Glycoprotein Inhibitor Properties
P-glycoprotein (P-gp) is a protein belonging to the ATP-binding cassette (ABC) transporters superfamily that has clinical relevance due to its role in drug metabolism and multi-drug resistance (MDR) in several human pathogens and diseases. P-gp is a major cause of drug resistance in cancer, parasiti...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-01-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/12/1/525 |