A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis.

Thrombocytopenia is a serious issue connected with the pathogenesis of several human diseases including chronic inflammation, arthritis, Alzheimer's disease, cardiovascular diseases (CVDs) and other oxidative stress-associated pathologies. The indiscriminate use of antibiotics and other biologi...

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Bibliographic Details
Main Authors: Kodagahalli S Rakesh, Swamy Jagadish, Ajjampura C Vinayaka, Mahadevappa Hemshekhar, Manoj Paul, Ram M Thushara, Mahalingam S Sundaram, Toreshettahally R Swaroop, Chakrabhavi D Mohan, Basappa, Marilinganadoddi P Sadashiva, Kempaiah Kemparaju, Kesturu S Girish, Kanchugarakoppal S Rangappa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169656?pdf=render