Reproductive status of Onchocerca volvulus after ivermectin treatment in an ivermectin-naïve and a frequently treated population from Cameroon.

For two decades, onchocerciasis control has been based on mass treatment with ivermectin (IVM), repeated annually or six-monthly. This drug kills Onchocerca volvulus microfilariae (mf) present in the skin and the eyes (microfilaricidal effect) and prevents for 3-4 months the release of new mf by adu...

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Main Authors: Hugues C Nana-Djeunga, Catherine Bourguinat, Sébastien D Pion, Jean Bopda, Jonas A Kengne-Ouafo, Flobert Njiokou, Roger K Prichard, Samuel Wanji, Joseph Kamgno, Michel Boussinesq
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3998936?pdf=render