Efficacy and safety of short-term use of a pelubiprofen CR and aceclofenac in patients with symptomatic knee osteoarthritis: A double-blinded, randomized, multicenter, active drug comparative, parallel-group, phase IV, non-inferiority clinical trial.

Efficacy and safety of short-term use of a pelubiprofen CR and aceclofenac in patients with symptomatic knee osteoarthritis: A double-blinded, randomized, multicenter, active drug comparative, parallel-group, phase IV, non-inferiority clinical trial.

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<h4>Introduction</h4>At present, information about clinical efficacy and adverse events of controlled release (CR) form of pelubiprofen, a prodrug of 2-arylopropionic acid with relatively selective effects on cyclooxygenase-2 activity, remains scarce. In this study, we sought to determin...

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Bibliographic Details
Main Authors: Joung Youp Shin, Moon Jong Chang, Myung Ku Kim, Seung-Baik Kang, Kang-Il Kim, Hee Gon Park, Sahnghoon Lee, Sung-Hwan Kim, Seung-Beom Han, Han Jun Lee, Young-Wan Moon, Jae-Doo Yoo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238024

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https://doi.org/10.1371/journal.pone.0238024

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