How to Tackle Underdeterminacy in Metabolic Flux Analysis? A Tutorial and Critical Review
Metabolic flux analysis is often (not to say almost always) faced with system underdeterminacy. Indeed, the linear algebraic system formed by the steady-state mass balance equations around the intracellular metabolites and the equality constraints related to the measurements of extracellular fluxes...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Processes |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9717/9/9/1577 |