Delayed anti-TNF therapy increases the risk of total knee replacement in patients with severe rheumatoid arthritis

Abstract Background This study evaluated the effect of early anti-tumor necrosis factor (TNF) therapy in patients with severe rheumatoid arthritis (RA) on the subsequent risk of total knee replacement (TKR) surgery. Methods This retrospective observational study included a hospital-based cohort of 2...

Full description

Bibliographic Details
Main Authors: Ying-Chou Chen, Wen-Chan Chiu, Tien-Tsai Cheng, Han-Ming Lai, Shan-Fu Yu, Ben Yu-Jih Su, Chung-Yuan Hsu, Chi-Hua Ko, Jia-Feng Chen
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
RA
TKR
Online Access:http://link.springer.com/article/10.1186/s12891-017-1685-z