β-Hairpin Peptide Mimics Decrease Human Islet Amyloid Polypeptide (hIAPP) Aggregation

β-Hairpin Peptide Mimics Decrease Human Islet Amyloid Polypeptide (hIAPP) Aggregation

Amyloid diseases are degenerative pathologies, highly prevalent today because they are closely related to aging, that have in common the erroneous folding of intrinsically disordered proteins (IDPs) which aggregate and lead to cell death. Type 2 Diabetes involves a peptide called human islet amyloid...

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Bibliographic Details
Main Authors: Jacopo Lesma, Faustine Bizet, Corentin Berardet, Nicolo Tonali, Sara Pellegrino, Myriam Taverna, Lucie Khemtemourian, Jean-Louis Soulier, Carine van Heijenoort, Frédéric Halgand, Tâp Ha-Duong, Julia Kaffy, Sandrine Ongeri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
amyloid
hIAPP
type 2 diabetes
peptidomimetics
β-hairpin
aza-peptide
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.729001/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.729001/full

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