Imatinib is active in glioblastoma multiforme expressing platelet-derived growth factor receptor

Imatinib is active in glioblastoma multiforme expressing platelet-derived growth factor receptor

Objective: To report on 15 patients with recurrent anaplastic astrocytoma (AA) or glioblastoma multiforme (GBM) previously treated with standard therapies and, then, treated with imatinib. Methods: Fifteen consecutive patients with recurrent AA or GBM, positive immunostaining for the PDGF-alpha and...

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Bibliographic Details
Main Authors: Fabiana Viola, Jaques Tabacof, Rene Cláudio Gansl, Rober Abramoff, Artur Katz, Carlos Henrique Barrios, Sergio Daniel Simon
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2008-09-01
Series:Einstein (São Paulo)
Subjects:
Astrocytoma/drug therapy
Brain neoplasms/drug therapy
Glioblastoma/therapy
Piperazines/therapeutic use
Receptors
platelet-derived growth factor
Online Access:http://www.einstein.br/revista/arquivos/PDF/338-Einsteinv6n2p115-9.pdf

Internet

http://www.einstein.br/revista/arquivos/PDF/338-Einsteinv6n2p115-9.pdf

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