N-Acetyl Cysteine Ameliorates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease and Intracellular Triglyceride Accumulation by Preserving Mitochondrial Function

N-Acetyl Cysteine Ameliorates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease and Intracellular Triglyceride Accumulation by Preserving Mitochondrial Function

Rationale: Nonalcoholic fatty liver disease (NAFLD) is a kind of metabolic disease characterized by liver steatosis. Excessive reactive oxygen species (ROS) originating from dysfunctional mitochondria is the major pathophysiological contributor in the development of NAFLD and is thought to be a prom...

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Bibliographic Details
Main Authors: Weijian Hang, Hongyang Shu, Zheng Wen, Jinyan Liu, Zhiyuan Jin, Zeqi Shi, Chen Chen, Dao Wen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
NAC
NAFLD
mitochondria
PGC1a
SIRT1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.636204/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.636204/full

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