Structural determinants of PINK1 topology and dual subcellular distribution
<p>Abstract</p> <p>Background</p> <p>PINK1 is a mitochondria-targeted kinase that constitutively localizes to both the mitochondria and the cytosol. The mechanism of how PINK1 achieves cytosolic localization following mitochondrial processing remains unknown. Understand...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-11-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/11/90 |