Amphiphilic Block Copolymer Microspheres Derived from Castor Oil, Poly(ε-carpolactone), and Poly(ethylene glycol): Preparation, Characterization and Application in Naltrexone Drug Delivery

Amphiphilic Block Copolymer Microspheres Derived from Castor Oil, Poly(ε-carpolactone), and Poly(ethylene glycol): Preparation, Characterization and Application in Naltrexone Drug Delivery

In the present study, the newly synthesized castor oil-derived thioether-containing ω-hydroxyacid (TEHA) block copolymers with polycaprolactone (TEHA-b-PCL), with methoxypoly(ethylene glycol) (mPEG), (TEHA-b-mPEG) and with poly(ethylene glycol) (PEG) (TEHA-b-PEG-b-TEHA), were investigated...

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Bibliographic Details
Main Authors: Maria Nerantzaki, Eirini Skoufa, Kyriakos-Vasileios Adam, Stavroula Nanaki, Apostolos Avgeropoulos, Margaritis Kostoglou, Dimitrios Bikiaris
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Materials
Subjects:
castor oil
poly(ε-caprolactone)
poly(ethylene glycol)
amphiphilic block copolymers
microspheres
naltrexone
drug release
Online Access:http://www.mdpi.com/1996-1944/11/10/1996

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http://www.mdpi.com/1996-1944/11/10/1996

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