Tumor mutation burden: from comprehensive mutational screening to the clinic

Tumor mutation burden: from comprehensive mutational screening to the clinic

Abstract The recent advent of immunomodulatory therapies into the clinic has demanded the identification of innovative predictive biomarkers to identify patients most likely to respond to immunotherapy and support the design of tailored clinical trials. Current molecular testing for selection of pat...

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Bibliographic Details
Main Authors: Francesca Galuppini, Carlo Alberto Dal Pozzo, Jutta Deckert, Fotios Loupakis, Matteo Fassan, Raffaele Baffa
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cancer Cell International
Subjects:
Tumor mutation burden
Immunotherapy
Next generation sequencing
Target therapy
Online Access:http://link.springer.com/article/10.1186/s12935-019-0929-4

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http://link.springer.com/article/10.1186/s12935-019-0929-4

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