Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells

Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells

Donepezil is a potent and selective acetylcholinesterase inhibitor developed for the treatment of Alzheimer’s disease. To elucidate whether donepezil causes neuronal differentiation, we examined its effect on nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells. Donepezil (10 µM) signif...

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Bibliographic Details
Main Authors: Toru Oda, Toshiaki Kume, Hiroshi Katsuki, Tetsuhiro Niidome, Hachiro Sugimoto, Akinori Akaike
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319342331

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http://www.sciencedirect.com/science/article/pii/S1347861319342331

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