Metabolic profiling provides a system understanding of hypothyroidism in rats and its application.

BACKGROUND: Hypothyroidism is a chronic condition of endocrine disorder and its precise molecular mechanism remains obscure. In spite of certain efficacy of thyroid hormone replacement therapy in treating hypothyroidism, it often results in other side effects because of its over-replacement, so it i...

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Bibliographic Details
Main Authors: Si Wu, Guangguo Tan, Xin Dong, Zhenyu Zhu, Wuhong Li, Ziyang Lou, Yifeng Chai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567130?pdf=render