Application of a scalable plant transient gene expression platform for malaria vaccine development

Application of a scalable plant transient gene expression platform for malaria vaccine development

Despite decades of intensive research efforts there is currently no vaccine that provides sustained sterile immunity against malaria. In this context, a large number of targets from the different stages of the Plasmodium falciparum life cycle have been evaluated as vaccine candidates. None of these...

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Bibliographic Details
Main Authors: Holger eSpiegel, Alexander eBoes, Nadja eVoepel, Veronique eBeiss, Gueven eEdgue, Thomas eRademacher, Markus eSack, Stefan eSchillberg, Andreas eReimann, Rainer eFischer
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Plant Science
Subjects:
Plasmodium falciparum
Heat stability
Red fluorescent protein
Expression screening
multi domain-fusion antigens
Nicotiana benthamiana plants
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2015.01169/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpls.2015.01169/full

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