Microfluidics for minute DNA sample analysis: open challenges for genetic testing of cell-free circulating DNA in blood plasma

Genetic testing based on the analysis of circulating cell-free DNA (cfDNA) in body fluids, especially blood plasma, is raising interest for the management and follow-up of many diseases, including cancer. Because the concentration of cfDNA is low and its composition mostly degraded, this material ca...

Full description

Bibliographic Details
Main Authors: Rémi Malbec, Jean Cacheux, Pierre Cordelier, Thierry Leichlé, Pierre Joseph, Aurélien Bancaud
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Micro and Nano Engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2590007218300054