Sixty hertz neurostimulation amplifies subthalamic neural synchrony in Parkinson's disease.

High frequency subthalamic nucleus (STN) deep brain stimulation (DBS) improves the cardinal motor signs of Parkinson's disease (PD) and attenuates STN alpha/beta band neural synchrony in a voltage-dependent manner. While there is a growing interest in the behavioral effects of lower frequency (...

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Bibliographic Details
Main Authors: Zack Blumenfeld, Anca Velisar, Mandy Miller Koop, Bruce C Hill, Lauren A Shreve, Emma J Quinn, Camilla Kilbane, Hong Yu, Jaimie M Henderson, Helen Brontë-Stewart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373818?pdf=render