A permutation-based non-parametric analysis of CRISPR screen data

A permutation-based non-parametric analysis of CRISPR screen data

Abstract Background Clustered regularly-interspaced short palindromic repeats (CRISPR) screens are usually implemented in cultured cells to identify genes with critical functions. Although several methods have been developed or adapted to analyze CRISPR screening data, no single specific algorithm h...

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Bibliographic Details
Main Authors: Gaoxiang Jia, Xinlei Wang, Guanghua Xiao
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Genomics
Subjects:
Functional genomics
False discovery rate
RNA interference
Negative selection
Next generation sequencing
Positive selection
Online Access:http://link.springer.com/article/10.1186/s12864-017-3938-5

Internet

http://link.springer.com/article/10.1186/s12864-017-3938-5

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