Mesenchymal stem cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture.

Mesenchymal stem cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture.

Renovascular hypertension induced by 2 Kidney-1 Clip (2K-1C) is a renin-angiotensin-system (RAS)-dependent model, leading to renal vascular rarefaction and renal failure. RAS inhibitors are not able to reduce arterial pressure (AP) and/or preserve the renal function, and thus, alternative therapies...

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Bibliographic Details
Main Authors: Elizabeth B Oliveira-Sales, Edgar Maquigussa, Patricia Semedo, Luciana G Pereira, Vanessa M Ferreira, Niels O Câmara, Cassia T Bergamaschi, Ruy R Campos, Mirian A Boim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817204?pdf=render

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