Mesenchymal stem cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture.

Renovascular hypertension induced by 2 Kidney-1 Clip (2K-1C) is a renin-angiotensin-system (RAS)-dependent model, leading to renal vascular rarefaction and renal failure. RAS inhibitors are not able to reduce arterial pressure (AP) and/or preserve the renal function, and thus, alternative therapies...

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Bibliographic Details
Main Authors: Elizabeth B Oliveira-Sales, Edgar Maquigussa, Patricia Semedo, Luciana G Pereira, Vanessa M Ferreira, Niels O Câmara, Cassia T Bergamaschi, Ruy R Campos, Mirian A Boim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817204?pdf=render