Exosomes derived from bone marrow mesenchymal stem cells promote osteosarcoma development by activating oncogenic autophagy

Osteosarcoma (OS) is a malignant bone tumor that frequently occurs in adolescents. It has a high rate of pulmonary metastasis and mortality. Previous studies have demonstrated that human bone marrow mesenchymal stem cells (hBMSCs) can promote the malignant progression in various tumors, including OS...

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Bibliographic Details
Main Authors: Yao Huang, Wei Liu, Bing He, Lei Wang, Fucheng Zhang, Hao Shu, Luning Sun
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137419302337