Trypsin Induced Degradation of Amyloid Fibrils

Trypsin Induced Degradation of Amyloid Fibrils

Proteolytic enzymes are known to be involved in the formation and degradation of various monomeric proteins, but the effect of proteases on the ordered protein aggregates, amyloid fibrils, which are considered to be extremely stable, remains poorly understood. In this work we study resistance to pro...

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Bibliographic Details
Main Authors: Olga V. Stepanenko, Maksim I. Sulatsky, Ekaterina V. Mikhailova, Olesya V. Stepanenko, Irina M. Kuznetsova, Konstantin K. Turoverov, Anna I. Sulatskaya
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
amyloid fibrils
proteolytic degradation
trypsin
stability
fragmentation
cytotoxicity
Online Access:https://www.mdpi.com/1422-0067/22/9/4828

Internet

https://www.mdpi.com/1422-0067/22/9/4828

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