Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)
Abstract Background Microglia-driven cerebral spreading inflammation is a key contributor to secondary brain injury after SAH. Genetic depletion or deactivation of microglia has been shown to ameliorate neuronal cell death. Therefore, clinically feasible anti-inflammatory approaches counteracting mi...
Main Authors: | Rebecca Heinz, Susan Brandenburg, Melina Nieminen-Kelhä, Irina Kremenetskaia, Philipp Boehm-Sturm, Peter Vajkoczy, Ulf C. Schneider |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02085-3 |
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