Species D Adenoviruses as Oncolytic Viral Vectors

Oncolytic adenoviruses (Ad) have shown promising results in the therapeutic treatment of cancer. Ad type 5 (Ad5) is the most extensively utilized Ad type. However, several limitations exist to using Ad5 as an oncolytic virus, including high levels of anti-Ad5 neutralizing antibodies in the populatio...

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Bibliographic Details
Main Authors: Brianna L. Bullard, Brigette N. Corder, Eric A. Weaver
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/12/1399