Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells

<p>Abstract</p> <p>Background</p> <p>A critical therapeutic challenge in epithelial ovarian carcinoma is the development of chemoresistance among tumor cells following exposure to first line chemotherapeutics. The molecular and genetic changes that drive the development...

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Bibliographic Details
Main Authors: Ali Mourad W, Hurst Jillian H, Altman Molly K, Callihan Phillip, Hooks Shelley B, Murph Mandi M
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/289