Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative model

Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative model

Abstract Background The established role miRNA-mRNA regulation of gene expression has in oncogenesis highlights the importance of integrating miRNA with downstream mRNA targets. These findings call for investigations aimed at identifying disease-associated miRNA-mRNA pairs. Hierarchical integrative...

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Bibliographic Details
Main Authors: Rency S. Varghese, Yuan Zhou, Megan Barefoot, Yifan Chen, Cristina Di Poto, Abdalla Kara Balla, Everett Oliver, Zaki A. Sherif, Deepak Kumar, Alexander H. Kroemer, Mahlet G. Tadesse, Habtom W. Ressom
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Medical Genomics
Subjects:
miRNA
mRNA
Hierarchical integrative model
Pathway analysis
hepatocellular carcinoma
Next generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12920-020-0706-1

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http://link.springer.com/article/10.1186/s12920-020-0706-1

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