Design and Synthesis of New Chacones Substituted with Azide/Triazole Groups and Analysis of Their Cytotoxicity Towards HeLa Cells

Design and Synthesis of New Chacones Substituted with Azide/Triazole Groups and Analysis of Their Cytotoxicity Towards HeLa Cells

A series of new chalcones substituted with azide/triazole groups were designed and synthesized, and their cytotoxic activity was evaluated <em>in vitro</em> against the HeLa cell line. <em>O</em>-Alkylation, Claisen-Schmidt condensation and Cu(...

Full description

Bibliographic Details
Main Authors: José A. F. P. Villar, Gustavo H. R. Viana, Leandro A. Barbosa, Fernando P. Varotti, Sarah C. Simões, Andersson Barison, Estrela M. P. V. E. Souza, Marina G. da Silva, Graziele D. da Silva
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Molecules
Subjects:
chalcone
cycloaddition
<em>O</em>-alkylation
HeLa cells
Online Access:http://www.mdpi.com/1420-3049/17/9/10331

Internet

http://www.mdpi.com/1420-3049/17/9/10331

Similar Items