Lamin-A interacting protein Hsp90 is required for DNA damage repair and chemoresistance of ovarian cancer cells
Abstract Ovarian cancer is the most malignant gynecologic cancer. Previous studies found that lamin-A was associated with DNA damage repair proteins but the underlying mechanism remains unclear. We speculate that this may be related to its interacting proteins, such as Hsp90. The aim of this study i...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04074-z |