Further investigations of the W-test for pairwise epistasis testing [version 1; referees: 2 approved]

Background: In a recent paper, a novel W-test for pairwise epistasis testing was proposed that appeared, in computer simulations, to have higher power than competing alternatives. Application to genome-wide bipolar data detected significant epistasis between SNPs in genes of relevant biological func...

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Bibliographic Details
Main Authors: Richard Howey, Heather J. Cordell
Format: Article
Language:English
Published: Wellcome 2017-07-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/2-54/v1