Completing sparse and disconnected protein-protein network by deep learning

Completing sparse and disconnected protein-protein network by deep learning

Abstract Background Protein-protein interaction (PPI) prediction remains a central task in systems biology to achieve a better and holistic understanding of cellular and intracellular processes. Recently, an increasing number of computational methods have shifted from pair-wise prediction to network...

Full description

Bibliographic Details
Main Authors: Lei Huang, Li Liao, Cathy H. Wu
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Bioinformatics
Subjects:
Disconnected protein interaction network
Neural network
Interaction prediction
Network evolution
Regularized Laplacian
Online Access:http://link.springer.com/article/10.1186/s12859-018-2112-7

Internet

http://link.springer.com/article/10.1186/s12859-018-2112-7

Similar Items