The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast.

Heterochromatin preferentially assembles at repetitive DNA elements, playing roles in transcriptional silencing, recombination suppression, and chromosome segregation. The RNAi machinery is required for heterochromatin assembly in a diverse range of organisms. In fission yeast, RNA splicing factors...

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Bibliographic Details
Main Authors: Scott P Kallgren, Stuart Andrews, Xavier Tadeo, Haitong Hou, James J Moresco, Patricia G Tu, John R Yates, Peter L Nagy, Songtao Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4038458?pdf=render