Effect of TET inhibitor on bovine parthenogenetic embryo development.

DNA demethylation catalysed by the ten-eleven translocation (TET) protein is an important step during extensive global epigenetic reprogramming in mammals. However, whether TET proteins play a key role in DNA demethylation during the development of bovine pre-implanted embryos is still unclear. In t...

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Bibliographic Details
Main Authors: Jian Zhang, Sheng Zhang, Yutian Wang, Hui Cheng, Linlin Hao, Yanhui Zhai, Zhiren Zhang, Xinglan An, Xiaoling Ma, Xueming Zhang, Ziyi Li, Bo Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739418?pdf=render