High-Throughput Assessment of Drug Cardiac Safety Using a High-Speed Impedance Detection Technology-Based Heart-on-a-Chip

Drug cardiac safety assessments play a significant role in drug discovery. Drug-induced cardiotoxicity is one of the main reasons for drug attrition, even when antiarrhythmic drugs can otherwise effectively treat the arrhythmias. Consequently, efficient drug preclinical assessments are needed in the...

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Bibliographic Details
Main Authors: Xi Zhang, Tianxing Wang, Ping Wang, Ning Hu
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Micromachines
Subjects:
Online Access:http://www.mdpi.com/2072-666X/7/7/122