Pancreatic β cell microRNA-26a alleviates type 2 diabetes by improving peripheral insulin sensitivity and preserving β cell function.

Type 2 diabetes (T2D) is characterized by insulin resistance along with pancreatic β cell failure. β cell factors are traditionally thought to control glucose homeostasis by modulating insulin levels, not insulin sensitivity. Exosomes are emerging as new regulators of intercellular communication. Ho...

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Bibliographic Details
Main Authors: Haixia Xu, Xiao Du, Jia Xu, Yu Zhang, Yan Tian, Geng Liu, Xiuxuan Wang, Meilin Ma, Wenya Du, Yu Liu, Lunzhi Dai, Wendong Huang, Nanwei Tong, Yuquan Wei, Xianghui Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000603