Gain of DNA methylation is enhanced in the absence of CTCF at the human <it>retinoblastoma </it>gene promoter
<p>Abstract</p> <p>Background</p> <p>Long-term gene silencing throughout cell division is generally achieved by DNA methylation and other epigenetic processes. Aberrant DNA methylation is now widely recognized to be associated with cancer and other human diseases. Here...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-06-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/11/232 |