Gain of DNA methylation is enhanced in the absence of CTCF at the human <it>retinoblastoma </it>gene promoter

<p>Abstract</p> <p>Background</p> <p>Long-term gene silencing throughout cell division is generally achieved by DNA methylation and other epigenetic processes. Aberrant DNA methylation is now widely recognized to be associated with cancer and other human diseases. Here...

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Bibliographic Details
Main Authors: Recillas-Targa Félix, Ayala-Ortega Erandi, Valdes-Quezada Christian, González-Buendía Edgar, Furlan-Magaril Mayra, Dávalos-Salas Mercedes
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/232