Metabolic reprogramming by Zika virus provokes inflammation in human placenta

Zika virus (ZIKV) infection of pregnant women is associated with pregnancy loss and birth defects, but molecular insights for the aetiology are scarce. Here the authors show that ZIKV reprograms the host lipidome to facilitate viral replication, induce mitochondria dysfunction, and cause immune imba...

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Bibliographic Details
Main Authors: Qian Chen, Jordi Gouilly, Yann J. Ferrat, Ana Espino, Quentin Glaziou, Géraldine Cartron, Hicham El Costa, Reem Al-Daccak, Nabila Jabrane-Ferrat
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16754-z