BiSpark: a Spark-based highly scalable aligner for bisulfite sequencing data

BiSpark: a Spark-based highly scalable aligner for bisulfite sequencing data

Abstract Background Bisulfite sequencing is one of the major high-resolution DNA methylation measurement method. Due to the selective nucleotide conversion on unmethylated cytosines after treatment with sodium bisulfite, processing bisulfite-treated sequencing reads requires additional steps which n...

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Bibliographic Details
Main Authors: Seokjun Soe, Yoonjae Park, Heejoon Chae
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Bioinformatics
Subjects:
DNA methylation
Bisulfite sequencing
Alignment
Apache Spark
Online Access:http://link.springer.com/article/10.1186/s12859-018-2498-2

Internet

http://link.springer.com/article/10.1186/s12859-018-2498-2

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