Spatial Distribution of Mycobacterium ulcerans in Buruli Ulcer Lesions: Implications for Laboratory Diagnosis.

Spatial Distribution of Mycobacterium ulcerans in Buruli Ulcer Lesions: Implications for Laboratory Diagnosis.

BACKGROUND:Current laboratory diagnosis of Buruli ulcer (BU) is based on microscopic detection of acid fast bacilli, quantitative real-time PCR (qPCR), histopathology or cultivation. Insertion sequence (IS) 2404 qPCR, the most sensitive method, is usually only available at reference laboratories. Th...

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Main Authors: Marie-Thérèse Ruf, Miriam Bolz, Moritz Vogel, Pierre F Bayi, Martin W Bratschi, Ghislain Emmanuel Sopho, Dorothy Yeboah-Manu, Alphonse Um Boock, Thomas Junghanss, Gerd Pluschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4890796?pdf=render

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http://europepmc.org/articles/PMC4890796?pdf=render

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